St. Louis cannbis culture has grown tremendously. A few years ago you could only find a handful of events happening in the month of April. Now April is officially the biggest month for cannabis events in St. Louis , and 2026 is bringing next-level energy. From 420 weekend festivals  to infused food competitions to street festivals , parties, dispensary pop-ups, and exclusive experiences—this is your ultimate guide to the best 420 events in St. Louis . If you’re searching for